| Gene Information | |
|---|---|
| Gene Name | TEAD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 426 |
| Protein Names | Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000187079 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P28347 |
| Gene Card | TEAD1 |
| Uniprot ID | P28347 |
| Pfam | PF01285; PF17725 |
| In ASD | yes |
| Allosteric Prediction | no (-1.000198243) |
| Ortholog in Animals | Alpaca_ TEAD1 ( ortholog_one2one ) Dog_ TEAD1 ( ortholog_one2one ) GuineaPig_ TEAD1 ( ortholog_one2one ) Macaque_ TEAD1 ( ortholog_one2one ) Mouse_ Tead1 ( ortholog_one2one ) Pig_ TEAD1 ( ortholog_one2one ) Rat_ Tead1 ( ortholog_one2one ) Rabbit_ TEAD1 ( ortholog_one2one ) |
| Ohnologs | TEAD2, TEAD4, TEAD3 |
| Paralogs | TEAD3, TEAD4, TEAD2 |
| Tissue | NA |
| Tissue Specificity | Preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2HZD (NMR - ) 3KYS (X-ray 2.80A ) 4RE1 (X-ray 2.20A ) 4Z8E (X-ray 2.09A ) 5NNX (X-ray 3.29A ) 6HIL (X-ray 2.30A ) 6IM5 (X-ray 1.70A ) 7CMM (X-ray 3.50A ) 7ZJP (X-ray 2.19A ) |
| DBSNP | rs11567847 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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