| Gene Information | |
|---|---|
| Gene Name | TDRKH |
| Organism | Homo sapiens (Human) |
| Gene Length | 561 |
| Protein Names | Tudor and KH domain-containing protein (Tudor domain-containing protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000182134 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y2W6 |
| Gene Card | TDRKH |
| Uniprot ID | Q9Y2W6 |
| Pfam | PF00013; PF00567 |
| In ASD | no |
| Allosteric Prediction | no (-1.172818505) |
| Ortholog in Animals | Alpaca_ TDRKH ( ortholog_one2one ) Dog_ TDRKH ( ortholog_one2one ) GuineaPig_ TDRKH ( ortholog_one2one ) Macaque_ TDRKH ( ortholog_one2one ) Mouse_ Tdrkh ( ortholog_one2one ) Pig_ TDRKH ( ortholog_one2one ) Rat_ Tdrkh ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TDRD5, TDRD7, TDRD1, TDRD6, TDRD10, TDRD15 |
| Tissue | cerebellar.hemisphere, cerebellum, testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DIQ (NMR - ) 3FDR (X-ray 1.75A ) 5J39 (X-ray 1.95A ) 6B57 (X-ray 1.93A ) 6PI7 (X-ray 2.80A ) |
| DBSNP | rs17853082 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q80VL1}. Mitochondrion {ECO:0000250|UniProtKB:Q80VL1}. Note=Probable component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Colocalizes with pi- and piP-bodies, a subset of the nuage which contains secondary piRNAs. Associated with mitochondria in the germline. {ECO:0000250|UniProtKB:Q80VL1}. |
| Mouse PG classification | NA |
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