| Gene Information | |
|---|---|
| Gene Name | TDRD9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1382 |
| Protein Names | ATP-dependent RNA helicase TDRD9 (EC 3.6.4.13) (Tudor domain-containing protein 9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000156414 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NDG6 |
| Gene Card | TDRD9 |
| Uniprot ID | Q8NDG6 |
| Pfam | PF00270; PF04408; PF00271; PF00567 |
| In ASD | no |
| Allosteric Prediction | no (-0.493225566) |
| Ortholog in Animals | Alpaca_ TDRD9 ( ortholog_one2one ) Dog_ TDRD9 ( ortholog_one2one ) GuineaPig_ TDRD9 ( ortholog_one2one ) Macaque_ TDRD9 ( ortholog_one2one ) Mouse_ Tdrd9 ( ortholog_one2one ) Pig_ TDRD9 ( ortholog_one2one ) Rat_ Tdrd9 ( ortholog_one2one ) Rabbit_ TDRD9 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | YTHDC2, DHX40, DHX34, DHX32, HELB, DHX57, DHX30, DHX29, DHX36, DHX15, DHX35, DHX9, DHX38, DQX1, DHX16, DHX33, DHX8, DHX37 |
| Tissue | testis, thyroid |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:28536242}. Nucleus {ECO:0000250|UniProtKB:Q14BI7}. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to piP-bodies, a subset of the nuage which contains secondary piRNAs. PIWIL2 is required for its localization to piP-bodies. {ECO:0000250|UniProtKB:Q14BI7}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |