| Gene Information | |
|---|---|
| Gene Name | TDRD6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2096 |
| Protein Names | Tudor domain-containing protein 6 (Antigen NY-CO-45) (Cancer/testis antigen 41.2) (CT41.2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000180113 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O60522 |
| Gene Card | TDRD6 |
| Uniprot ID | O60522 |
| Pfam | PF00567 |
| In ASD | no |
| Allosteric Prediction | no (-1.446159821) |
| Ortholog in Animals | Alpaca_ TDRD6 ( ortholog_one2one ) Dog_ TDRD6 ( ortholog_one2one ) GuineaPig_ TDRD6 ( ortholog_one2one ) Macaque_ TDRD6 ( ortholog_one2one ) Mouse_ Tdrd6 ( ortholog_one2one ) Pig_ TDRD6 ( ortholog_one2one ) Rat_ Tdrd6 ( ortholog_one2one ) Rabbit_ TDRD6 ( ortholog_one2one ) |
| Ohnologs | TDRD15 |
| Paralogs | TDRD5, TDRD7, TDRKH, TDRD1, TDRD10, TDRD15 |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7750596 rs3799277 rs9463234 rs9381472 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:P61407}. Note=Present in chromatoid body (CB) of spermatids, also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids. Colocalizes in CB with DDX4, PIWIL1, PIWIL2, TDRD1 and TDRD7. {ECO:0000250|UniProtKB:P61407}. |
| Mouse PG classification | NA |
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