| Gene Information | |
|---|---|
| Gene Name | TDRD3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 651 |
| Protein Names | Tudor domain-containing protein 3 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000083544 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H7E2 |
| Gene Card | TDRD3 |
| Uniprot ID | Q9H7E2 |
| Pfam | PF08585; PF00567; PF00627 |
| In ASD | no |
| Allosteric Prediction | no (-0.718038873) |
| Ortholog in Animals | Alpaca_ TDRD3 ( ortholog_one2one ) Dog_ TDRD3 ( ortholog_one2one ) GuineaPig_ TDRD3 ( ortholog_one2one ) Macaque_ TDRD3 ( ortholog_one2one ) Mouse_ Tdrd3 ( ortholog_one2one ) Pig_ TDRD3 ( ortholog_one2one ) Rat_ Tdrd3 ( ortholog_one2one ) Rabbit_ TDRD3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:18664458}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WJI (NMR - ) 2LTO (NMR - ) 3PMT (X-ray 1.80A ) 3PNW (X-ray 2.05A ) 3S6W (X-ray 1.78A ) 5GVD (X-ray 1.62A ) 5GVE (X-ray 3.61A ) 5YJ8 (X-ray 1.76A ) 6V9T (X-ray 2.15A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18632687}. Nucleus {ECO:0000269|PubMed:21172665}. Note=Predominantly cytoplasmic. Associated with actively translating polyribosomes and with mRNA stress granules. {ECO:0000269|PubMed:18632687, ECO:0000269|PubMed:18664458}. |
| Mouse PG classification | NA |
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