| Gene Information | |
|---|---|
| Gene Name | TCRZ |
| Organism | Homo sapiens (Human) |
| Gene Length | 164 |
| Protein Names | T-cell surface glycoprotein CD3 zeta chain (T-cell receptor T3 zeta chain) (CD antigen CD247) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P20963 |
| Gene Card | CD247 |
| Uniprot ID | P20963 |
| Pfam | PF02189; PF11628 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | CD3Z is expressed in normal lymphoid tissue and in peripheral blood mononuclear cells (PBMCs) (PubMed:11722641). {ECO:0000269|PubMed:11722641}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1TCE (NMR - ) 1YGR (X-ray 2.90A ) 2HAC (NMR - ) 2OQ1 (X-ray 1.90A ) 3IK5 (X-ray 2.05A ) 3IOZ (X-ray 3.70A ) 4XZ1 (X-ray 2.80A ) 6JXR (EM 3.70A ) 7FJD (EM 3.20A ) 7FJE (EM 3.00A ) 7FJF (EM 3.10A ) 7PHR (EM 3.08A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:P24161}; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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