| Gene Information | |
|---|---|
| Gene Name | TCN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 427 |
| Protein Names | Transcobalamin-2 (TC-2) (Transcobalamin II) (TC II) (TCII) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000185339 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P20062 |
| Gene Card | TCN2 |
| Uniprot ID | P20062 |
| Pfam | PF01122; PF14478 |
| In ASD | no |
| Allosteric Prediction | yes (0.252698264) |
| Ortholog in Animals | Alpaca_ TCN2 ( ortholog_one2one ) Dog_ TCN2 ( ortholog_one2one ) GuineaPig_ TCN2 ( ortholog_one2one ) Macaque_ TCN2 ( ortholog_one2one ) Mouse_ Tcn2 ( ortholog_one2one ) Pig_ TCN2 ( ortholog_one2one ) Rat_ Tcn2 ( ortholog_one2one ) Rabbit_ TCN2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TCN1, CBLIF |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2BB5 (X-ray 3.20A ) 4ZRP (X-ray 2.10A ) 4ZRQ (X-ray 2.60A ) 5NO0 (X-ray 1.57A ) 5NP4 (X-ray 1.43A ) 5NRP (X-ray 1.57A ) 5NSA (X-ray 1.27A ) 7QBD (X-ray 4.18A ) 7QBE (X-ray 3.00A ) 7QBF (X-ray 1.85A ) 7QBG (X-ray 2.69A ) |
| DBSNP | rs9606756 rs35915865 rs35838082 rs17849434 rs1801198 rs9621049 rs1131603 rs4820889 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:3782074, ECO:0000269|PubMed:8443384}. |
| Mouse PG classification | NA |
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