| Gene Information | |
|---|---|
| Gene Name | TCF7L1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 588 |
| Protein Names | Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000152284 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9HCS4 |
| Gene Card | TCF7L1 |
| Uniprot ID | Q9HCS4 |
| Pfam | PF08347; PF00505 |
| In ASD | no |
| Allosteric Prediction | no (-0.270990839) |
| Ortholog in Animals | Alpaca_ TCF7L1 ( ortholog_one2one ) Dog_ TCF7L1 ( ortholog_one2one ) GuineaPig_ TCF7L1 ( ortholog_one2one ) Macaque_ TCF7L1 ( ortholog_one2one ) Mouse_ Tcf7l1 ( ortholog_one2one ) Rat_ Tcf7l1 ( ortholog_one2one ) Rabbit_ TCF7L1 ( ortholog_one2one ) |
| Ohnologs | TCF7, LEF1, TCF7L2 |
| Paralogs | TCF7, TCF7L2, LEF1 |
| Tissue | NA |
| Tissue Specificity | Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium. {ECO:0000269|PubMed:9916915}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11547160 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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