| Gene Information | |
|---|---|
| Gene Name | ADH5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 374 |
| Protein Names | Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase 5) (Alcohol dehydrogenase class chi chain) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284) |
| Target Name | alcohol dehydrogenase class-3 |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000197894 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P11766 |
| Gene Card | ADH5 |
| Uniprot ID | P11766 |
| Pfam | PF08240; PF00107 |
| In ASD | no |
| Allosteric Prediction | yes (0.3413922) |
| Ortholog in Animals | Alpaca_ ADH5 ( ortholog_one2one ) Dog_ ADH5 ( ortholog_one2many ) GuineaPig_ ADH5 ( ortholog_one2one ) Macaque_ ADH5 ( ortholog_one2one ) Mouse_ Adh5 ( ortholog_one2one ) Pig_ ADH5 ( ortholog_one2many ) Rat_ Adh5 ( ortholog_one2one ) Rabbit_ ADH5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MECR, CRYZ, RTN4IP1, PTGR2, TP53I3, CRYZL1, PTGR3, ADH6, ADH4, SORD, ADH1B, ADH1A, ADH1C, VAT1L, PTGR1, ADH7, VAT1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1M6H (X-ray 2.00A ) 1M6W (X-ray 2.30A ) 1MA0 (X-ray 2.30A ) 1MC5 (X-ray 2.60A ) 1MP0 (X-ray 2.20A ) 1TEH (X-ray 2.70A ) 2FZE (X-ray 1.90A ) 2FZW (X-ray 1.84A ) 3QJ5 (X-ray 1.90A ) |
| DBSNP | rs28730623 rs754853545 rs28730628 rs16996593 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
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