| Gene Information | |
|---|---|
| Gene Name | GOSR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 212 |
| Protein Names | Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000108433 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O14653 |
| Gene Card | GOSR2 |
| Uniprot ID | O14653 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.76648999) |
| Ortholog in Animals | Alpaca_ GOSR2 ( ortholog_one2one ) Dog_ GOSR2 ( ortholog_one2one ) GuineaPig_ GOSR2 ( ortholog_one2one ) Macaque_ GOSR2 ( ortholog_one2one ) Mouse_ Gosr2 ( ortholog_one2one ) Pig_ GOSR2 ( ortholog_one2one ) Rat_ Gosr2 ( ortholog_one2one ) Rabbit_ GOSR2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | VTI1B, VTI1A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3EG9 (X-ray 3.00A ) |
| DBSNP | rs197922 rs387906881 |
| Subcellular location [CC] | Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:21549339}; Single-pass type IV membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:9349823}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O35165}. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus. {ECO:0000250|UniProtKB:O35165}. |
| Mouse PG classification | NA |
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