| Gene Information | |
|---|---|
| Gene Name | GPR17 |
| Organism | Homo sapiens (Human) |
| Gene Length | 367 |
| Protein Names | Uracil nucleotide/cysteinyl leukotriene receptor (UDP/CysLT receptor) (G-protein coupled receptor 17) (P2Y-like receptor) (R12) |
| Target Name | uracil nucleotide/cysteinyl leukotriene receptor |
| Target Type | Literature-reported target |
| Gene Age | 544 ( ENSG00000144230 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q13304 |
| Gene Card | GPR17 |
| Uniprot ID | Q13304 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.057497825) |
| Ortholog in Animals | Alpaca_ GPR17 ( ortholog_one2one ) Dog_ GPR17 ( ortholog_one2one ) GuineaPig_ GPR17 ( ortholog_one2one ) Macaque_ GPR17 ( ortholog_one2one ) Mouse_ Gpr17 ( ortholog_one2one ) Pig_ GPR17 ( ortholog_one2one ) Rat_ Gpr17 ( ortholog_one2one ) Rabbit_ GPR17 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GPR20, LPAR4, LPAR6, P2RY10, GPR35, GPR55, F2RL2, P2RY8, F2RL1, F2R, F2RL3, GPR18, CYSLTR2, CYSLTR1, GPR65, GPR4 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain. {ECO:0000269|PubMed:16990797}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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