| Gene Information | |
|---|---|
| Gene Name | TBX2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 712 |
| Protein Names | T-box transcription factor TBX2 (T-box protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000121068 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q13207 |
| Gene Card | TBX2 |
| Uniprot ID | Q13207 |
| Pfam | PF00907; PF12598 |
| In ASD | no |
| Allosteric Prediction | no (-0.352967792) |
| Ortholog in Animals | Alpaca_ TBX2 ( ortholog_one2one ) Dog_ TBX2 ( ortholog_one2one ) GuineaPig_ TBX2 ( ortholog_one2one ) Macaque_ TBX2 ( ortholog_one2one ) Mouse_ Tbx2 ( ortholog_one2one ) Pig_ TBX2 ( ortholog_one2one ) Rat_ Tbx2 ( ortholog_one2one ) Rabbit_ TBX2 ( ortholog_one2one ) |
| Ohnologs | TBX3 |
| Paralogs | TBX5, TBX15, TBR1, TBX20, EOMES, TBX21, MGA, TBX4, TBX19, TBXT, TBX6, TBX3, TBX18, TBX22, TBX1, TBX10 |
| Tissue | NA |
| Tissue Specificity | Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1364709483 rs1555877071 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:29726930, ECO:0000305|PubMed:11111039}. |
| Mouse PG classification | NA |
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