| Gene Information | |
|---|---|
| Gene Name | TBCD |
| Organism | Homo sapiens (Human) |
| Gene Length | 1192 |
| Protein Names | Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000141556 ) 3 ( ENSG00000278759 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BTW9 |
| Gene Card | TBCD |
| Uniprot ID | Q9BTW9 |
| Pfam | PF12612 |
| In ASD | no |
| Allosteric Prediction | no (-0.31661348) |
| Ortholog in Animals | Alpaca_ TBCD ( ortholog_one2one ) Dog_ TBCD ( ortholog_one2one ) GuineaPig_ TBCD ( ortholog_one2one ) Macaque_ TBCD ( ortholog_one2one ) Mouse_ Tbcd ( ortholog_one2one ) Pig_ TBCD ( ortholog_one2one ) Rat_ Tbcd ( ortholog_one2one ) Rabbit_ TBCD ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:10231032, ECO:0000269|PubMed:11110777}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.047059(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs778417127 rs953299085 rs764085684 rs886041086 rs775014444 rs1567999844 rs2292971 rs749225304 rs181969865 rs886041085 rs3214033 rs886041087 rs8072406 rs867484272 rs764003906 rs755177846 rs2292969 |
| Subcellular location [CC] | Cell junction, tight junction {ECO:0000250|UniProtKB:Q28205}. Lateral cell membrane {ECO:0000250|UniProtKB:Q28205}. Cytoplasm {ECO:0000250|UniProtKB:Q28205}. Cell junction, adherens junction {ECO:0000250|UniProtKB:Q28205}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:27666370}. Note=Localized in cell-cell contacts. {ECO:0000250|UniProtKB:Q28205}. |
| Mouse PG classification | NA |
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