| Gene Information | |
|---|---|
| Gene Name | TBCC |
| Organism | Homo sapiens (Human) |
| Gene Length | 346 |
| Protein Names | Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000124659 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15814 |
| Gene Card | TBCC |
| Uniprot ID | Q15814 |
| Pfam | PF07986; PF16752 |
| In ASD | no |
| Allosteric Prediction | no (-0.8802484) |
| Ortholog in Animals | Alpaca_ TBCC ( ortholog_one2one ) Dog_ TBCC ( ortholog_one2one ) Macaque_ TBCC ( ortholog_one2one ) Mouse_ Tbcc ( ortholog_one2one ) Pig_ TBCC ( ortholog_one2one ) Rat_ Tbcc ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the retina. Expressed in the rod and cone photoreceptors, extending from the inner segments (IS), through the outer nuclear layer (ONL) and into the synapses in the outer plexiform layer (OPL). Strongly expressed to the photoreceptor connecting cilium at the tips of the IS (at protein level). {ECO:0000269|PubMed:12417528}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2L3L (NMR - ) 2YUH (NMR - ) |
| DBSNP | rs2234026 rs144361927 rs7742995 rs2234027 rs2234028 rs12175072 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12417528}. Note=Detected predominantly in the photoreceptor connecting cilium. |
| Mouse PG classification | NA |
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