| Gene Information | |
|---|---|
| Gene Name | TBCB |
| Organism | Homo sapiens (Human) |
| Gene Length | 244 |
| Protein Names | Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000105254 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q99426 |
| Gene Card | TBCB |
| Uniprot ID | Q99426 |
| Pfam | PF01302; PF14560 |
| In ASD | no |
| Allosteric Prediction | no (-0.716603105) |
| Ortholog in Animals | Alpaca_ TBCB ( ortholog_one2one ) Dog_ TBCB ( ortholog_one2one ) GuineaPig_ TBCB ( ortholog_one2one ) Macaque_ TBCB ( ortholog_one2one ) Mouse_ Tbcb ( ortholog_one2one ) Pig_ TBCB ( ortholog_one2one ) Rat_ Tbcb ( ortholog_one2one ) Rabbit_ TBCB ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Found in most tissues. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.01(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15831477, ECO:0000269|PubMed:22777741}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:15831477}. Note=Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone. {ECO:0000269|PubMed:15831477}. |
| Mouse PG classification | NA |
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