Gene Information
Gene NameSNRPB
OrganismHomo sapiens (Human)
Gene Length240
Protein NamesSmall nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/B') (SmB/B')
Target NameNA
Target TypeNA
Gene Age1714 ( ENSG00000125835 )
Evolutionary StageEukaryota
AlphaFoldDBP14678
Gene CardSNRPB
Uniprot IDP14678
PfamPF01423
In ASDno
Allosteric Predictionno (-1.04974896)
Ortholog in AnimalsAlpaca_ SNRPB ( ortholog_one2one )
GuineaPig_ SNRPB ( ortholog_one2one )
Macaque_ SNRPB ( ortholog_one2one )
Mouse_ Snrpb ( ortholog_one2one )
Rat_ Snrpb ( ortholog_one2one )
OhnologsNA
ParalogsSNRPN
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.197209(Rat);0.011842(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1D3B  (X-ray  2.00A  )  3CW1  (X-ray  5.49A  )  3JCR  (EM  7.00A  )  3PGW  (X-ray  4.40A  )  4PJO  (X-ray  3.30A  )  4WZJ  (X-ray  3.60A  )  5MQF  (EM  5.90A  )  5O9Z  (EM  4.50A  )  5XJC  (EM  3.60A  )  5YZG  (EM  4.10A  )  5Z56  (EM  5.10A  )  5Z57  (EM  6.50A  )  5Z58  (EM  4.90A  )  6AH0  (EM  5.70A  )  6FF7  (EM  4.50A  )  6ICZ  (EM  3.00A  )  6ID0  (EM  2.90A  )  6ID1  (EM  2.86A  )  6QDV  (EM  3.30A  )  6QW6  (EM  2.92A  )  6QX9  (EM  3.28A  )  6V4X  (EM  3.20A  )  6Y53  (EM  7.10A  )  6Y5Q  (EM  7.10A  )  7A5P  (EM  5.00A  )  7ABG  (EM  7.80A  )  7ABI  (EM  8.00A  )  7DVQ  (EM  2.89A  )  7EVO  (EM  2.50A  )  7W59  (EM  3.60A  )  7W5A  (EM  3.60A  )  7W5B  (EM  4.30A  ) 
DBSNP rs11545672 
Subcellular location [CC]Cytoplasm, cytosol {ECO:0000269|PubMed:18984161}. Nucleus {ECO:0000269|PubMed:11574479, ECO:0000269|PubMed:11991638, ECO:0000269|PubMed:26912367, ECO:0000269|PubMed:28076346, ECO:0000269|PubMed:28502770, ECO:0000269|PubMed:28781166}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. {ECO:0000305}.
Mouse PG classificationNA
click here to return to the previous page