| Gene Information | |
|---|---|
| Gene Name | TAX1BP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 124 |
| Protein Names | Tax1-binding protein 3 (Glutaminase-interacting protein 3) (Tax interaction protein 1) (TIP-1) (Tax-interacting protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000213977 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O14907 |
| Gene Card | TAX1BP3 |
| Uniprot ID | O14907 |
| Pfam | PF00595; PF02163 |
| In ASD | no |
| Allosteric Prediction | no (-0.756480622) |
| Ortholog in Animals | Alpaca_ TAX1BP3 ( ortholog_one2one ) Dog_ TAX1BP3 ( ortholog_one2one ) GuineaPig_ TAX1BP3 ( ortholog_one2one ) Macaque_ TAX1BP3 ( ortholog_one2one ) Mouse_ Tax1bp3 ( ortholog_one2one ) Pig_ TAX1BP3 ( ortholog_one2one ) Rat_ Tax1bp3 ( ortholog_one2one ) Rabbit_ TAX1BP3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Detected in brain, heart, kidney, lung, small intestine and skeletal muscle. Detected in various cell lines including HeLa. Weakly expressed in peripheral blood leukocytes. {ECO:0000269|PubMed:10940294, ECO:0000269|PubMed:16855024, ECO:0000269|PubMed:25645515}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KG2 (NMR - ) 2L4S (NMR - ) 2L4T (NMR - ) 2VZ5 (X-ray 1.74A ) 3GJ9 (X-ray 2.80A ) 3SFJ (X-ray 1.24A ) 4E3B (X-ray 1.50A ) 4NNL (X-ray 1.50A ) 4NNM (X-ray 1.60A ) |
| DBSNP | rs1057517690 |
| Subcellular location [CC] | Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the cell membrane by interaction with membrane proteins. |
| Mouse PG classification | NA |
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