| Gene Information | |
|---|---|
| Gene Name | ACP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 423 |
| Protein Names | Lysosomal acid phosphatase (LAP) (EC 3.1.3.2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000134575 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P11117 |
| Gene Card | ACP2 |
| Uniprot ID | P11117 |
| Pfam | PF00328 |
| In ASD | no |
| Allosteric Prediction | no (-0.311235161) |
| Ortholog in Animals | Alpaca_ ACP2 ( ortholog_one2one ) Dog_ ACP2 ( ortholog_one2one ) GuineaPig_ ACP2 ( ortholog_one2one ) Macaque_ ACP2 ( ortholog_one2many ) Mouse_ Acp2 ( ortholog_one2one ) Pig_ ACP2 ( ortholog_one2one ) Rat_ Acp2 ( ortholog_one2one ) Rabbit_ ACP2 ( ortholog_one2one ) |
| Ohnologs | ACP4, ACP3 |
| Paralogs | ACP4, FRA10AC1, ACP6, PXYLP1, ACP3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2167079 rs34425282 rs4647764 |
| Subcellular location [CC] | Lysosome membrane {ECO:0000269|PubMed:2684640, ECO:0000269|PubMed:3056714}; Single-pass membrane protein {ECO:0000255}; Lumenal side {ECO:0000305|PubMed:2684640, ECO:0000305|PubMed:3056714}. Lysosome lumen. Note=The soluble form arises by proteolytic processing of the membrane-bound form. {ECO:0000269|PubMed:2684640, ECO:0000269|PubMed:3056714}. |
| Mouse PG classification | LPG |
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