| Gene Information | |
|---|---|
| Gene Name | TASK |
| Organism | Homo sapiens (Human) |
| Gene Length | 394 |
| Protein Names | Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1) (Two pore K(+) channel KT3.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O14649 |
| Gene Card | KCNK3 |
| Uniprot ID | O14649 |
| Pfam | PF07885 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6RV2 (X-ray 3.00A ) 6RV3 (X-ray 2.90A ) 6RV4 (X-ray 3.10A ) |
| DBSNP | rs1085307438 rs398123040 rs398123042 rs398123043 rs398123039 rs398123041 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:23169818}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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