| Gene Information | |
|---|---|
| Gene Name | SF3A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 793 |
| Protein Names | Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000099995 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15459 |
| Gene Card | SF3A1 |
| Uniprot ID | Q15459 |
| Pfam | PF12230; PF01805; PF00240 |
| In ASD | no |
| Allosteric Prediction | no (-1.000506905) |
| Ortholog in Animals | Alpaca_ SF3A1 ( ortholog_one2one ) Dog_ SF3A1 ( ortholog_one2one ) GuineaPig_ SF3A1 ( ortholog_one2one ) Macaque_ SF3A1 ( ortholog_one2one ) Mouse_ Sf3a1 ( ortholog_one2one ) Pig_ SF3A1 ( ortholog_one2one ) Rat_ Sf3a1 ( ortholog_one2one ) Rabbit_ SF3A1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. |
| Pharmacological Animal Models | 0.325390(Chimpanzee);0.078800(Mouse);0.197225(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1ZKH (NMR - ) 2DT6 (NMR - ) 2DT7 (NMR - ) 5Z56 (EM 5.10A ) 5Z57 (EM 6.50A ) 5Z58 (EM 4.90A ) 6AH0 (EM 5.70A ) 6AHD (EM 3.80A ) 6FF7 (EM 4.50A ) 6QX9 (EM 3.28A ) 6Y53 (EM 7.10A ) 6Y5Q (EM 7.10A ) 7ABG (EM 7.80A ) 7ABI (EM 8.00A ) 7EVO (EM 2.50A ) 7P08 (NMR - ) 7P0V (X-ray 1.56A ) |
| DBSNP | rs765594577 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:10882114, ECO:0000269|PubMed:29360106, ECO:0000269|PubMed:30315277}. Nucleus speckle {ECO:0000269|PubMed:21349847}. |
| Mouse PG classification | NA |
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