| Gene Information | |
|---|---|
| Gene Name | TARS3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 802 |
| Protein Names | Threonine--tRNA ligase 2, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000185418 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | A2RTX5 |
| Gene Card | TARS3 |
| Uniprot ID | A2RTX5 |
| Pfam | PF03129; PF02824; PF00587; PF07973 |
| In ASD | no |
| Allosteric Prediction | no (-0.778464329) |
| Ortholog in Animals | Alpaca_ TARS3 ( ortholog_one2one ) Dog_ TARS3 ( ortholog_one2one ) GuineaPig_ TARS3 ( ortholog_one2one ) Macaque_ TARS3 ( ortholog_one2one ) Mouse_ Tarsl2 ( ortholog_one2one ) Pig_ TARS3 ( ortholog_one2one ) Rat_ Tars3 ( ortholog_one2one ) Rabbit_ TARS3 ( ortholog_one2one ) |
| Ohnologs | TARS1, TARS2 |
| Paralogs | TARS2, MRPL39, PARS2, TARS1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q8BLY2}. Nucleus {ECO:0000250|UniProtKB:Q8BLY2}. Note=Primarily cytoplasmic. Also detected at lower levels in the nucleus. {ECO:0000250|UniProtKB:Q8BLY2}. |
| Mouse PG classification | NA |
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