| Gene Information | |
|---|---|
| Gene Name | TBRG4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 631 |
| Protein Names | FAST kinase domain-containing protein 4 (Cell cycle progression restoration protein 2) (Cell cycle progression protein 2) (Protein TBRG4) (Transforming growth factor beta regulator 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000136270 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q969Z0 |
| Gene Card | TBRG4 |
| Uniprot ID | Q969Z0 |
| Pfam | PF06743; PF08368; PF08373 |
| In ASD | no |
| Allosteric Prediction | no (-1.028341418) |
| Ortholog in Animals | Alpaca_ TBRG4 ( ortholog_one2one ) Dog_ TBRG4 ( ortholog_one2one ) GuineaPig_ TBRG4 ( ortholog_one2one ) Macaque_ TBRG4 ( ortholog_one2one ) Mouse_ Tbrg4 ( ortholog_one2one ) Pig_ TBRG4 ( ortholog_one2one ) Rat_ Tbrg4 ( ortholog_one2one ) Rabbit_ TBRG4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FASTKD2, FASTK, FASTKD3, FASTKD5, FASTKD1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed (PubMed:12759187). Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in smooth muscle (PubMed:20869947). {ECO:0000269|PubMed:12759187, ECO:0000269|PubMed:20869947}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2304694 rs2304693 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:20869947, ECO:0000269|PubMed:28335001}. |
| Mouse PG classification | NA |
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