Gene Information
Gene NameTAF8
OrganismHomo sapiens (Human)
Gene Length310
Protein NamesTranscription initiation factor TFIID subunit 8 (Protein taube nuss) (TBP-associated factor 43 kDa) (TBP-associated factor 8) (Transcription initiation factor TFIID 43 kDa subunit) (TAFII-43) (TAFII43) (hTAFII43)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000137413 )
Evolutionary StageEukaryota
AlphaFoldDBQ7Z7C8
Gene CardTAF8
Uniprot IDQ7Z7C8
PfamPF07524; PF10406
In ASDno
Allosteric Predictionno (-0.555315019)
Ortholog in AnimalsAlpaca_ TAF8 ( ortholog_one2one )
Dog_ TAF8 ( ortholog_one2one )
GuineaPig_ TAF8 ( ortholog_one2one )
Macaque_ TAF8 ( ortholog_one2one )
Mouse_ Taf8 ( ortholog_one2one )
Pig_ TAF8 ( ortholog_one2one )
Rat_ AABR07064983.1 ( ortholog_one2many )
Rat_ Taf8 ( ortholog_one2many )
Rabbit_ TAF8 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4WV4  (X-ray  1.91A  4WV6  (X-ray  1.75A  5FUR  (EM  8.50A  6MZC  (EM  4.50A  6MZL  (EM  23.00A  6MZM  (EM  7.50A  7EDX  (EM  4.50A  7EG7  (EM  6.20A  7EG8  (EM  7.40A  7EG9  (EM  3.70A  7EGA  (EM  4.10A  7EGB  (EM  3.30A  7EGC  (EM  3.90A  7EGD  (EM  6.75A  7EGE  (EM  9.00A  7EGG  (EM  2.77A  7EGH  (EM  3.04A  7EGI  (EM  9.82A  7EGJ  (EM  8.64A  7ENA  (EM  4.07A  7ENC  (EM  4.13A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:14580349}. Cytoplasm {ECO:0000250}. Note=Localized in the cytoplasm and transported from the cytoplasm to the nucleus in some cells, possibly depending on the functional or developmental state of the cell. {ECO:0000250}.
Mouse PG classificationNA
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