Gene Information
Gene NameTAF6
OrganismHomo sapiens (Human)
Gene Length677
Protein NamesTranscription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000106290 )
Evolutionary StageEukaryota
AlphaFoldDBP49848
Gene CardTAF6
Uniprot IDP49848
PfamPF02969; PF07571
In ASDno
Allosteric Predictionno (-0.693368857)
Ortholog in AnimalsAlpaca_ TAF6 ( ortholog_one2one )
Dog_ TAF6 ( ortholog_one2one )
GuineaPig_ TAF6 ( ortholog_one2one )
Macaque_ TAF6 ( ortholog_one2one )
Mouse_ Taf6 ( ortholog_one2one )
Pig_ TAF6 ( ortholog_one2one )
Rat_ Taf6 ( ortholog_one2one )
Rabbit_ TAF6 ( ortholog_one2one )
OhnologsNA
ParalogsTAF6L
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.070427(Rat);0.103128(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5FUR  (EM  8.50A  6F3T  (X-ray  2.50A  6MZC  (EM  4.50A  6MZD  (EM  9.80A  6MZL  (EM  23.00A  6MZM  (EM  7.50A  7EDX  (EM  4.50A  7EG7  (EM  6.20A  7EG8  (EM  7.40A  7EG9  (EM  3.70A  7EGA  (EM  4.10A  7EGB  (EM  3.30A  7EGC  (EM  3.90A  7EGD  (EM  6.75A  7EGE  (EM  9.00A  7EGF  (EM  3.16A  7EGG  (EM  2.77A  7EGH  (EM  3.04A  7EGI  (EM  9.82A  7EGJ  (EM  8.64A  7ENA  (EM  4.07A  7ENC  (EM  4.13A 
DBSNP rs4134897  rs727503778  rs374993554 
Subcellular location [CC]Nucleus.;
[Isoform 4]: Nucleus {ECO:0000269|PubMed:18628956}.
Mouse PG classificationNA
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