| Gene Information | |
|---|---|
| Gene Name | TAF4B |
| Organism | Homo sapiens (Human) |
| Gene Length | 862 |
| Protein Names | Transcription initiation factor TFIID subunit 4B (Transcription initiation factor TFIID 105 kDa subunit) (TAF(II)105) (TAFII-105) (TAFII105) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000141384 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q92750 |
| Gene Card | TAF4B |
| Uniprot ID | Q92750 |
| Pfam | PF05236; PF07531 |
| In ASD | no |
| Allosteric Prediction | no (-0.191279248) |
| Ortholog in Animals | Alpaca_ TAF4B ( ortholog_one2one ) Dog_ TAF4B ( ortholog_one2one ) GuineaPig_ TAF4B ( ortholog_one2one ) Macaque_ TAF4B ( ortholog_one2one ) Mouse_ Taf4b ( ortholog_one2one ) Pig_ TAF4B ( ortholog_one2one ) Rat_ Taf4b ( ortholog_one2one ) Rabbit_ TAF4B ( ortholog_one2one ) |
| Ohnologs | TAF4 |
| Paralogs | TAF4 |
| Tissue | NA |
| Tissue Specificity | Preferentially expressed in ovarian granulosa cells (at protein level). Highly expressed in B-cells. {ECO:0000269|PubMed:16088961, ECO:0000269|PubMed:8858156}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.110174(Rat);0.116854(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16942219 rs12963653 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11567023, ECO:0000269|PubMed:16088961}. Cytoplasm {ECO:0000269|PubMed:11567023, ECO:0000269|PubMed:16088961}. Note=Export into the cytoplasm is mediated by a CRM1-independent nuclear export pathway and not by phosphorylation. {ECO:0000269|PubMed:11567023}. |
| Mouse PG classification | NA |
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