| Gene Information | |
|---|---|
| Gene Name | TM4SF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 202 |
| Protein Names | Transmembrane 4 L6 family member 1 (Membrane component chromosome 3 surface marker 1) (Tumor-associated antigen L6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000169908 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P30408 |
| Gene Card | TM4SF1 |
| Uniprot ID | P30408 |
| Pfam | PF05805 |
| In ASD | no |
| Allosteric Prediction | no (-1.205441612) |
| Ortholog in Animals | Alpaca_ TM4SF1 ( ortholog_one2one ) Dog_ TM4SF1 ( ortholog_one2one ) GuineaPig_ TM4SF1 ( ortholog_one2one ) Macaque_ TM4SF1 ( ortholog_one2one ) Mouse_ Tm4sf1 ( ortholog_one2one ) Pig_ TM4SF1 ( ortholog_one2one ) Rat_ Tm4sf1 ( ortholog_one2one ) Rabbit_ TM4SF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TM4SF18, TM4SF4, TM4SF5, TM4SF20, TM4SF19 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some normal cells, endothelial cells in particular. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. Note=Colocalizes with SDCBP2 in the apical region of the cell (PubMed:11102519). {ECO:0000269|PubMed:11102519}. |
| Mouse PG classification | NA |
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