| Gene Information | |
|---|---|
| Gene Name | TACSTD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 323 |
| Protein Names | Tumor-associated calcium signal transducer 2 (Cell surface glycoprotein Trop-2) (Membrane component chromosome 1 surface marker 1) (Pancreatic carcinoma marker protein GA733-1) |
| Target Name | tumor associated calcium signal transducer 2 |
| Target Type | Clinical trial target |
| Gene Age | 680 ( ENSG00000184292 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P09758 |
| Gene Card | TACSTD2 |
| Uniprot ID | P09758 |
| Pfam | PF00086 |
| In ASD | no |
| Allosteric Prediction | no (-0.450625727) |
| Ortholog in Animals | Alpaca_ TACSTD2 ( ortholog_one2one ) Dog_ TACSTD2 ( ortholog_one2one ) Mouse_ Tacstd2 ( ortholog_one2one ) Pig_ TACSTD2 ( ortholog_one2one ) Rat_ Tacstd2 ( ortholog_one2one ) Rabbit_ TACSTD2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EPCAM |
| Tissue | NA |
| Tissue Specificity | Placenta, pancreatic carcinoma cell lines. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2MAE (NMR - ) 2MVK (NMR - ) 2MVL (NMR - ) 7E5M (X-ray 3.20A ) 7E5N (X-ray 3.20A ) 7PEE (X-ray 2.81A ) |
| DBSNP | rs1062964 rs35075952 rs14008 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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