| Gene Information | |
|---|---|
| Gene Name | SELPLG |
| Organism | Homo sapiens (Human) |
| Gene Length | 412 |
| Protein Names | P-selectin glycoprotein ligand 1 (PSGL-1) (Selectin P ligand) (CD antigen CD162) |
| Target Name | p-selectin glycoprotein ligand 1 |
| Target Type | Clinical trial target |
| Gene Age | 454 ( ENSG00000110876 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q14242 |
| Gene Card | SELPLG |
| Uniprot ID | Q14242 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.41852634) |
| Ortholog in Animals | Alpaca_ SELPLG ( ortholog_one2one ) Dog_ SELPLG ( ortholog_one2one ) Macaque_ SELPLG ( ortholog_one2one ) Mouse_ Selplg ( ortholog_one2one ) Rat_ Selplg ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed on neutrophils, monocytes and most lymphocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1G1S (X-ray 1.90A ) |
| DBSNP | rs2228315 rs63748999 rs8179142 rs756234416 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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