| Gene Information | |
|---|---|
| Gene Name | UBASH3A |
| Organism | Homo sapiens (Human) |
| Gene Length | 661 |
| Protein Names | Ubiquitin-associated and SH3 domain-containing protein A (Cbl-interacting protein 4) (CLIP4) (Suppressor of T-cell receptor signaling 2) (STS-2) (T-cell ubiquitin ligand 1) (TULA-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000160185 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P57075 |
| Gene Card | UBASH3A |
| Uniprot ID | P57075 |
| Pfam | PF00300; PF14604 |
| In ASD | no |
| Allosteric Prediction | yes (0.200871313) |
| Ortholog in Animals | Alpaca_ UBASH3A ( ortholog_one2one ) Dog_ UBASH3A ( ortholog_one2one ) GuineaPig_ UBASH3A ( ortholog_one2one ) Macaque_ UBASH3A ( ortholog_one2one ) Mouse_ Ubash3a ( ortholog_one2one ) Pig_ UBASH3A ( ortholog_one2one ) Rat_ Ubash3a ( ortholog_one2one ) Rabbit_ UBASH3A ( ortholog_one2one ) |
| Ohnologs | UBASH3B |
| Paralogs | UBASH3B |
| Tissue | appendix, lymph.node, lung |
| Tissue Specificity | Highest expression of UBASH3A in tissues belonging to the immune system, including spleen, peripheral blood leukocytes, thymus and bone marrow. {ECO:0000269|PubMed:11281453, ECO:0000269|PubMed:15107835}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CRN (NMR - ) 5WDI (X-ray 2.43A ) |
| DBSNP | rs2277798 rs2277800 rs775952011 rs13048049 rs13048049 rs17114930 |
| Subcellular location [CC] | Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
| click here to return to the previous page | |