| Gene Information | |
|---|---|
| Gene Name | TAC4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 113 |
| Protein Names | Tachykinin-4 (Preprotachykinin-C) (PPT-C) [Cleaved into: Endokinin-A (EKA); Endokinin-A/B (EKA/B); Endokinin-C (EKC)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000176358 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q86UU9 |
| Gene Card | TAC4 |
| Uniprot ID | Q86UU9 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.796379058) |
| Ortholog in Animals | Alpaca_ TAC4 ( ortholog_one2one ) Dog_ TAC4 ( ortholog_one2one ) Mouse_ Tac4 ( ortholog_one2one ) Pig_ TAC4 ( ortholog_one2one ) Rat_ Tac4 ( ortholog_one2one ) Rabbit_ TAC4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed at low levels in the uterus of both pregnant and non-pregnant women. Isoform 1 is found only in the adrenal gland and fetal liver. Isoform 2 is found in heart, liver, bone marrow, prostate, adrenal gland and testis. Isoform 3 and isoform 4 are expressed predominantly in adrenal gland and placenta. {ECO:0000269|PubMed:12716968, ECO:0000269|PubMed:12788812}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2MOC (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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