| Gene Information | |
|---|---|
| Gene Name | UBE1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1058 |
| Protein Names | Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P22314 |
| Gene Card | UBA1 |
| Uniprot ID | P22314 |
| Pfam | PF16191; PF16190; PF09358; PF00899; PF10585 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in erythrocytes (at protein level). Ubiquitous. {ECO:0000269|PubMed:1986373}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001390(Rat);0.035(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4P22 (X-ray 2.75A ) 6DC6 (X-ray 3.14A ) 7PYV (X-ray 3.27A ) |
| DBSNP | rs2070169 rs80356545 rs80356546 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:1376922}. Mitochondrion {ECO:0000269|PubMed:1376922}. Nucleus {ECO:0000269|PubMed:1376922, ECO:0000269|PubMed:22456334}.; [Isoform 1]: Nucleus {ECO:0000269|PubMed:33108101, ECO:0000269|PubMed:7528747, ECO:0000269|PubMed:9099746}.; [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:33108101, ECO:0000269|PubMed:7528747}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |