| Gene Information | |
|---|---|
| Gene Name | T |
| Organism | Homo sapiens (Human) |
| Gene Length | 435 |
| Protein Names | T-box transcription factor T (Brachyury protein) (Protein T) |
| Target Name | t-box transcription factor t |
| Target Type | Clinical trial target |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O15178 |
| Gene Card | TBXT |
| Uniprot ID | O15178 |
| Pfam | PF00907 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in testis, but not in other, normal tissues. Detected in lung tumors (at protein level). {ECO:0000269|PubMed:22611028, ECO:0000269|PubMed:30237576}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 5QRF (X-ray 2.03A ) 5QRG (X-ray 1.95A ) 5QRH (X-ray 1.81A ) 5QRI (X-ray 1.83A ) 5QRJ (X-ray 1.81A ) 5QRK (X-ray 1.63A ) 5QRL (X-ray 1.76A ) 5QRM (X-ray 1.55A ) 5QRN (X-ray 1.62A ) 5QRO (X-ray 1.61A ) 5QRP (X-ray 1.67A ) 5QRQ (X-ray 2.10A ) 5QRR (X-ray 1.69A ) 5QRS (X-ray 2.06A ) 5QRT (X-ray 1.77A ) 5QRU (X-ray 1.76A ) 5QRV (X-ray 1.67A ) 5QRW (X-ray 1.74A ) 5QRX (X-ray 1.87A ) 5QRY (X-ray 1.58A ) 5QRZ (X-ray 1.96A ) 5QS0 (X-ray 1.60A ) 5QS1 (X-ray 1.66A ) 5QS2 (X-ray 1.68A ) 5QS3 (X-ray 1.71A ) 5QS4 (X-ray 1.65A ) 5QS5 (X-ray 1.81A ) 5QS6 (X-ray 1.67A ) 5QS7 (X-ray 1.66A ) 5QS8 (X-ray 1.47A ) 5QS9 (X-ray 1.43A ) 5QSA (X-ray 1.55A ) 5QSB (X-ray 1.82A ) 5QSC (X-ray 1.62A ) 5QSD (X-ray 1.87A ) 5QSE (X-ray 2.01A ) 5QSF (X-ray 1.96A ) 5QSG (X-ray 1.87A ) 5QSH (X-ray 1.90A ) 5QSI (X-ray 1.64A ) 5QSJ (X-ray 1.49A ) 5QSK (X-ray 1.55A ) 5QSL (X-ray 2.20A ) 5QT0 (X-ray 2.10A ) 6F58 (X-ray 2.25A ) 6F59 (X-ray 2.15A ) 6ZU8 (X-ray 1.95A ) 7ZK2 (X-ray 1.60A ) 7ZKF (X-ray 1.49A ) 7ZL2 (X-ray 1.80A ) 8A10 (X-ray 1.88A ) |
| DBSNP | rs587777303 rs2305089 rs3127328 rs77703807 rs35292451 rs3816300 rs34517945 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:22611028, ECO:0000269|PubMed:24253444}. |
| Mouse PG classification | HPG |
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