Gene Information
Gene NameSYT6
OrganismHomo sapiens (Human)
Gene Length510
Protein NamesSynaptotagmin-6 (Synaptotagmin VI) (SytVI)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000134207 )
Evolutionary StageVertebrata
AlphaFoldDBQ5T7P8
Gene CardSYT6
Uniprot IDQ5T7P8
PfamPF00168
In ASDno
Allosteric Predictionno (-0.875552212)
Ortholog in AnimalsAlpaca_ SYT6 ( ortholog_one2one )
Dog_ SYT6 ( ortholog_one2one )
GuineaPig_ SYT6 ( ortholog_one2one )
Macaque_ SYT6 ( ortholog_one2one )
Mouse_ Syt6 ( ortholog_one2one )
Pig_ SYT6 ( ortholog_one2one )
Rat_ Syt6 ( ortholog_one2one )
Rabbit_ SYT6 ( ortholog_one2one )
OhnologsSYT10, SYT9, SYT3
ParalogsSYT2, SYTL3, SYT13, TC2N, SYT1, SYT7, SYTL4, SYTL5, DOC2B, DOC2A, SYT14, C2CD4C, SYTL1, RPH3A, SYT8, SYT4, SYT11, SYT12, C2CD4A, C2CD4B, RPH3AL, SYT15, SYT15B, SYT9, SYT16, C2CD4D, SYT3, SYTL2, SYT10, SYT5, SYT17
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q9R0N8};
Single-pass membrane protein {ECO:0000250|UniProtKB:Q9R0N8}.;
[Isoform 1]: Membrane {ECO:0000250|UniProtKB:Q9R0N8};
Single-pass membrane protein {ECO:0000250}. Note=Localized predominantly to endoplasmic reticulum (ER) and/or Golgi-like perinuclear compartment (By similarity). {ECO:0000250|UniProtKB:Q9R0N8}.;
[Isoform 2]: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9R0N8}. Cell membrane {ECO:0000250|UniProtKB:Q9R0N8};
Peripheral membrane protein {ECO:0000250|UniProtKB:Q9R0N8}.
Mouse PG classificationNA
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