| Gene Information | |
|---|---|
| Gene Name | KLHL42 |
| Organism | Homo sapiens (Human) |
| Gene Length | 505 |
| Protein Names | Kelch-like protein 42 (Cullin-3-binding protein 9) (Ctb9) (Kelch domain-containing protein 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000087448 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9P2K6 |
| Gene Card | KLHL42 |
| Uniprot ID | Q9P2K6 |
| Pfam | PF07707; PF01344 |
| In ASD | no |
| Allosteric Prediction | no (-1.12039018) |
| Ortholog in Animals | Alpaca_ KLHL42 ( ortholog_one2one ) Dog_ KLHL42 ( ortholog_one2one ) GuineaPig_ KLHL42 ( ortholog_one2one ) Macaque_ KLHL42 ( ortholog_one2one ) Mouse_ Klhl42 ( ortholog_one2one ) Pig_ KLHL42 ( ortholog_one2one ) Rat_ Klhl42 ( ortholog_one2one ) Rabbit_ KLHL42 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KLHL40, KLHDC7B, GAN, BACH1, KLHL20, KLHL10, KLHL21, KLHL32, KBTBD7, KBTBD6, BACH2, KLHL30, KLHL15, KLHL38, KLHL41, KLHL26, KLHL17, KBTBD3, KLHL13, KLHL9, KLHL18, KLHL23, KLHDC7A, KLHL31, IVNS1ABP, KLHL1, KEAP1, KLHL8, KLHL2, KLHL29, KBTBD12, KLHL34, KLHL7, KLHL33, KLHL36, KLHL28, KBTBD11, KLHL14, CCIN, BTBD18, IPP, KLHDC8B, KLHL6, KLHL24, KLHL5, KBTBD13, KBTBD8, KLHL3, KLHL35, KLHL22, KBTBD2, KLHL12, KLHL4, KLHDC8A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19261606}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:19261606}. Note=Predominantly in mitotic cells. Localized diffusely in the cytoplasm during the interphase. During metaphase is localized throughout the cell and more widely dispersed than the microtubules. In anaphase cells is localized between the two sets of separated chromosomes as well as at the spindle poles. During telophase is localized arround the nuclei of the two daughter cells. Not detected at the midbody region during cytokinesis. |
| Mouse PG classification | NA |
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