| Gene Information | |
|---|---|
| Gene Name | SYNPO |
| Organism | Homo sapiens (Human) |
| Gene Length | 929 |
| Protein Names | Synaptopodin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000171992 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8N3V7 |
| Gene Card | SYNPO |
| Uniprot ID | Q8N3V7 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.625940405) |
| Ortholog in Animals | Alpaca_ SYNPO ( ortholog_one2one ) Dog_ SYNPO ( ortholog_one2one ) GuineaPig_ SYNPO ( ortholog_one2one ) Macaque_ NDST1 ( ortholog_one2one ) Mouse_ Synpo ( ortholog_one2one ) Pig_ SYNPO ( ortholog_one2one ) Rat_ Myoz3 ( ortholog_one2one ) Rabbit_ SYNPO ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SYNPO2, SYNPO2L |
| Tissue | NA |
| Tissue Specificity | Expressed in cerebral cortex. {ECO:0000269|PubMed:9314539}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8CC35}. Cell junction, tight junction {ECO:0000250|UniProtKB:Q8CC35}. Perikaryon {ECO:0000250|UniProtKB:Q8CC35}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q8CC35}. Postsynaptic density {ECO:0000250|UniProtKB:Q8CC35}. Synapse {ECO:0000250|UniProtKB:Q8CC35}. Cytoplasm, cytosol {ECO:0000269|PubMed:30661770}. Note=Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses. {ECO:0000250|UniProtKB:Q8CC35}. |
| Mouse PG classification | NA |
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