| Gene Information | |
|---|---|
| Gene Name | ABCB9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 766 |
| Protein Names | ABC-type oligopeptide transporter ABCB9 (EC 7.4.2.6) (ATP-binding cassette sub-family B member 9) (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000150967 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NP78 |
| Gene Card | ABCB9 |
| Uniprot ID | Q9NP78 |
| Pfam | PF00664; PF00005 |
| In ASD | no |
| Allosteric Prediction | no (-0.794206657) |
| Ortholog in Animals | Alpaca_ ABCB9 ( ortholog_one2one ) Dog_ ABCB9 ( ortholog_one2one ) GuineaPig_ ABCB9 ( ortholog_one2one ) Macaque_ ABCB9 ( ortholog_one2one ) Mouse_ Abcb9 ( ortholog_one2one ) Pig_ ABCB9 ( ortholog_one2one ) Rat_ Abcb9 ( ortholog_one2one ) Rabbit_ ABCB9 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ABCB6, TAP1, ABCB11, ABCB4, ABCB8, TAP2, ABCB7, ABCB1, ABCB10, ABCB5 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis, and at moderate levels in brain, spinal cord, and thyroid. Not expressed in monocytes but strongly expressed during differentiation of monocytes to dendritic cells and macrophages. {ECO:0000269|PubMed:10748049, ECO:0000269|PubMed:17977821}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3803002 |
| Subcellular location [CC] | Lysosome membrane {ECO:0000269|PubMed:10748049, ECO:0000269|PubMed:15577206, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:17977821, ECO:0000269|PubMed:18175933, ECO:0000269|PubMed:18952056, ECO:0000269|PubMed:20377823, ECO:0000269|PubMed:21212514, ECO:0000269|PubMed:22641697, ECO:0000269|PubMed:30877195}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:10748049, ECO:0000269|PubMed:15577206, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:17977821, ECO:0000269|PubMed:18175933, ECO:0000269|PubMed:18952056, ECO:0000269|PubMed:20377823, ECO:0000269|PubMed:21212514}. Note=May be located in membrane rafts. Takes an intracellular route from the endoplasmic reticulum (ER), via Golgi and early endosomes to late endosomal and lysosomal compartments (PubMed:30877195). {ECO:0000269|PubMed:30877195}. |
| Mouse PG classification | NA |
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