| Gene Information | |
|---|---|
| Gene Name | SYNGAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1343 |
| Protein Names | Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000197283 ) 3 ( ENSG00000227460 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96PV0 |
| Gene Card | SYNGAP1 |
| Uniprot ID | Q96PV0 |
| Pfam | PF00168; PF12004; PF00616 |
| In ASD | no |
| Allosteric Prediction | no (-0.443902218) |
| Ortholog in Animals | Alpaca_ SYNGAP1 ( ortholog_one2one ) Dog_ SYNGAP1 ( ortholog_one2one ) GuineaPig_ SYNGAP1 ( ortholog_one2one ) Macaque_ SYNGAP1 ( ortholog_one2one ) Mouse_ Syngap1 ( ortholog_one2one ) Pig_ SYNGAP1 ( ortholog_one2one ) Rat_ Syngap1 ( ortholog_one2one ) Rabbit_ SYNGAP1 ( ortholog_one2one ) |
| Ohnologs | RASAL3, DAB2IP, RASAL2 |
| Paralogs | NF1, DAB2IP, RASAL1, RASA3, RASA1, RASA2, RASA4, RASA4B, RASAL2, RASAL3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.015873(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1057519546 rs1057519545 rs768682743 rs397514670 rs552867155 rs145472959 rs191549504 rs1396355432 rs796430835 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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