| Gene Information | |
|---|---|
| Gene Name | RNF130 |
| Organism | Homo sapiens (Human) |
| Gene Length | 419 |
| Protein Names | E3 ubiquitin-protein ligase RNF130 (EC 2.3.2.27) (Goliath homolog) (H-Goliath) (RING finger protein 130) (RING-type E3 ubiquitin transferase RNF130) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000113269 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86XS8 |
| Gene Card | RNF130 |
| Uniprot ID | Q86XS8 |
| Pfam | PF02225; PF13639 |
| In ASD | no |
| Allosteric Prediction | no (-0.512388827) |
| Ortholog in Animals | Alpaca_ RNF130 ( ortholog_one2one ) Dog_ RNF130 ( ortholog_one2one ) GuineaPig_ RNF130 ( ortholog_one2one ) Macaque_ RNF130 ( ortholog_one2one ) Mouse_ Rnf130 ( ortholog_one2one ) Pig_ RNF130 ( ortholog_one2one ) Rat_ AABR07029581.1 ( ortholog_one2one ) |
| Ohnologs | RNF128, RNF149, RNF150 |
| Paralogs | RNF133, RNF149, ZNRF4, RNF150, RNF215, RNF128, RNF167, RNF13, RNF148 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Highly expressed in leukocytes. Not expressed in erythroblasts. {ECO:0000269|PubMed:16549277}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:16549277}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |