| Gene Information | |
|---|---|
| Gene Name | SYCP2L |
| Organism | Homo sapiens (Human) |
| Gene Length | 812 |
| Protein Names | Synaptonemal complex protein 2-like (SCP-2-like) (145 kDa nucleolar protein homolog) (hsNO145) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000153157 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q5T4T6 |
| Gene Card | SYCP2L |
| Uniprot ID | Q5T4T6 |
| Pfam | PF18581; PF18584 |
| In ASD | no |
| Allosteric Prediction | no (-0.795537846) |
| Ortholog in Animals | Alpaca_ SYCP2L ( ortholog_one2one ) Dog_ SYCP2L ( ortholog_one2one ) Macaque_ SYCP2L ( ortholog_one2one ) Mouse_ Sycp2l ( ortholog_one2one ) Pig_ SYCP2L ( ortholog_one2one ) Rat_ AABR07027258.1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SYCP2 |
| Tissue | NA |
| Tissue Specificity | Expressed in the ovary (at protein level). {ECO:0000269|PubMed:17374641}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6456746 rs905595849 rs3798751 rs1225746 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:17374641}. Chromosome, centromere {ECO:0000269|PubMed:26362258}. Note=Localized to the synaptonemal complex lateral elements in late diplotene oocytes, while it is absent on the synaptonemal complex of leptotene, zygotene, pachytene and early diplotene oocytes (By similarity). Localizes to centromeres in dictyate oocytes (By similarity). Detected in nuclear granules and sizable aggregates (PubMed:17374641). {ECO:0000250|UniProtKB:A0A0M3U1B0, ECO:0000269|PubMed:17374641}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |