| Gene Information | |
|---|---|
| Gene Name | PTHR |
| Organism | Homo sapiens (Human) |
| Gene Length | 593 |
| Protein Names | Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q03431 |
| Gene Card | PTH1R |
| Uniprot ID | Q03431 |
| Pfam | PF00002; PF02793 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in most tissues. Most abundant in kidney, bone and liver. {ECO:0000269|PubMed:8397094}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1BL1 (NMR - ) 3C4M (X-ray 1.95A ) 3H3G (X-ray 1.94A ) 3L2J (X-ray 3.24A ) 4Z8J (X-ray 0.95A ) 5EMB (X-ray 0.85A ) 6NBF (EM 3.00A ) 6NBH (EM 3.50A ) 6NBI (EM 4.00A ) 7VVJ (EM 3.20A ) 7VVK (EM 3.30A ) 7VVL (EM 2.80A ) 7VVM (EM 3.20A ) 7VVN (EM 3.80A ) 7VVO (EM 4.10A ) |
| DBSNP | rs121434599 rs121434601 rs121434597 rs121434598 rs121434602 rs121434600 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:20172855, ECO:0000269|PubMed:8397094}; Multi-pass membrane protein {ECO:0000269|PubMed:20172855}. |
| Mouse PG classification | NA |
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