| Gene Information | |
|---|---|
| Gene Name | FGF13 |
| Organism | Homo sapiens (Human) |
| Gene Length | 245 |
| Protein Names | Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000129682 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q92913 |
| Gene Card | FGF13 |
| Uniprot ID | Q92913 |
| Pfam | PF00167 |
| In ASD | no |
| Allosteric Prediction | no (-0.313693943) |
| Ortholog in Animals | Mouse_ Fgf13 ( ortholog_one2one ) |
| Ohnologs | FGF16, FGF14, FGF9, FGF1, FGF12, FGF5, FGF7, FGF11 |
| Paralogs | FGF1, FGF16, FGF14, FGF21, FGF3, FGF10, FGF5, FGF9, FGF7, FGF22, FGF6, FGF23, FGF19, FGF17, FGF8, FGF18, FGF11, FGF12, FGF20, FGF2, FGF4 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Predominantly expressed in the nervous system. {ECO:0000269|PubMed:9232594}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3HBW (X-ray 1.90A ) 4DCK (X-ray 2.20A ) 4JPZ (X-ray 3.02A ) |
| DBSNP | rs2090039774 rs17510270 |
| Subcellular location [CC] | [Isoform 1]: Nucleus {ECO:0000269|PubMed:10644718}.; [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:10644718}. Nucleus {ECO:0000269|PubMed:10644718}.; [Isoform 3]: Cytoplasm {ECO:0000305|PubMed:10644718}. Nucleus {ECO:0000305|PubMed:10644718}.; [Isoform 4]: Cytoplasm {ECO:0000250|UniProtKB:P61329}. Nucleus {ECO:0000250|UniProtKB:P61329}.; [Isoform 5]: Cytoplasm {ECO:0000250|UniProtKB:P61329}. Nucleus {ECO:0000250|UniProtKB:P61329}.; Cell projection, filopodium {ECO:0000250|UniProtKB:P70377}. Cell projection, growth cone {ECO:0000250|UniProtKB:P70377}. Cell projection, dendrite {ECO:0000250|UniProtKB:P70377}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:P70377}. Cytoplasm {ECO:0000250|UniProtKB:P70377}. Note=Not secreted. Localizes to the lateral membrane and intercalated disks of myocytes. {ECO:0000250|UniProtKB:P70377}. |
| Mouse PG classification | NA |
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