| Gene Information | |
|---|---|
| Gene Name | SYB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 116 |
| Protein Names | Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P63027 |
| Gene Card | VAMP2 |
| Uniprot ID | P63027 |
| Pfam | PF00957 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Nervous system and skeletal muscle. {ECO:0000269|PubMed:8760387}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3FIE (X-ray 2.10A ) 3FII (X-ray 2.17A ) 3RK2 (X-ray 2.20A ) 3RK3 (X-ray 3.50A ) 3RL0 (X-ray 3.80A ) 7UDC (EM 3.70A ) |
| DBSNP | rs1598265387 rs1598265384 rs1598265382 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000269|PubMed:17313651}; Single-pass type IV membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:P63045}. Note=Colocalizes with PRKCZ and WDFY2 in intracellular vesicles (PubMed:17313651). {ECO:0000269|PubMed:17313651}. |
| Mouse PG classification | NA |
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