Gene Information
Gene NameSYAP1
OrganismHomo sapiens (Human)
Gene Length352
Protein NamesSynapse-associated protein 1 (BSD domain-containing signal transducer and Akt interactor protein) (BSTA)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000169895 )
Evolutionary StageEukaryota
AlphaFoldDBQ96A49
Gene CardSYAP1
Uniprot IDQ96A49
PfamPF03909
In ASDno
Allosteric Predictionno (-0.886139912)
Ortholog in AnimalsAlpaca_ SYAP1 ( ortholog_one2one )
Dog_ SYAP1 ( ortholog_one2one )
GuineaPig_ SYAP1 ( ortholog_one2one )
Macaque_ SYAP1 ( ortholog_one2one )
Mouse_ Syap1 ( ortholog_one2one )
Pig_ SYAP1 ( ortholog_one2one )
Rat_ Syap1 ( ortholog_one2one )
Rabbit_ SYAP1 ( ortholog_one2one )
OhnologsNA
ParalogsBSDC1
TissueNA
Tissue SpecificityExpressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas (PubMed:23300339). {ECO:0000269|PubMed:23300339}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1X3A  (NMR  -  ) 
DBSNP NA 
Subcellular location [CC]Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q9D5V6}. Golgi apparatus {ECO:0000250|UniProtKB:Q9D5V6}. Perikaryon {ECO:0000250|UniProtKB:Q9D5V6}. Cell projection, axon {ECO:0000250|UniProtKB:Q9D5V6}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9D5V6}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q9D5V6}. Presynaptic cell membrane {ECO:0000250|UniProtKB:Q9D5V6}. Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q9D5V6}. Membrane {ECO:0000269|PubMed:23300339}. Note=Localizes to cholinergic neuromuscular junctions and in actin-rich growth cone regions (By similarity). Membrane-associated in a epidermal growth factor (EGF)-dependent manner (PubMed:23300339). {ECO:0000250|UniProtKB:Q9D5V6, ECO:0000269|PubMed:23300339}.
Mouse PG classificationNA
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