| Gene Information | |
|---|---|
| Gene Name | TPP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 278 |
| Protein Names | Alpha-tocopherol transfer protein (Alpha-TTP) |
| Target Name | tripeptidyl-peptidase i |
| Target Type | Successful target |
| Gene Age | 645 ( ENSG00000166340 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P49638 |
| Gene Card | TTPA |
| Uniprot ID | P49638 |
| Pfam | PF00650; PF03765 |
| In ASD | no |
| Allosteric Prediction | yes (0.003642718) |
| Ortholog in Animals | Alpaca_ TPP1 ( ortholog_one2one ) Dog_ TPP1 ( ortholog_one2one ) GuineaPig_ TPP1 ( ortholog_one2one ) Macaque_ TPP1 ( ortholog_one2one ) Mouse_ Tpp1 ( ortholog_one2one ) Pig_ TPP1 ( ortholog_one2one ) Rat_ Tpp1 ( ortholog_one2one ) Rabbit_ TPP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1OIP (X-ray 1.95A ) 1OIZ (X-ray 1.88A ) 1R5L (X-ray 1.50A ) 5MUE (X-ray 2.40A ) 5MUG (X-ray 2.42A ) 6ZPD (X-ray 2.24A ) |
| DBSNP | rs397515522 rs121917849 rs143010236 rs397515524 rs34647756 rs121917850 rs35916840 rs397515526 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:7887897}. |
| Mouse PG classification | HPG |
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