| Gene Information | |
|---|---|
| Gene Name | SV2B |
| Organism | Homo sapiens (Human) |
| Gene Length | 683 |
| Protein Names | Synaptic vesicle glycoprotein 2B |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000185518 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q7L1I2 |
| Gene Card | SV2B |
| Uniprot ID | Q7L1I2 |
| Pfam | PF07690; PF13599; PF00083 |
| In ASD | no |
| Allosteric Prediction | no (-0.817519338) |
| Ortholog in Animals | Alpaca_ SV2B ( ortholog_one2one ) Dog_ SV2B ( ortholog_one2one ) GuineaPig_ SV2B ( ortholog_one2one ) Macaque_ SV2B ( ortholog_one2one ) Mouse_ Sv2b ( ortholog_one2one ) Pig_ SV2B ( ortholog_one2one ) Rat_ Sv2b ( ortholog_one2one ) Rabbit_ SV2B ( ortholog_one2one ) |
| Ohnologs | SV2C, SV2A |
| Paralogs | SV2A, SV2C |
| Tissue | brain, cerebral.cortex, cerebellar.hemisphere, cerebellum |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q63564}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q63564}. Note=Associated with synaptic-like microvesicles but not with insulin-containing vesicles in insulin-secreting cells of the pancreas (By similarity). Localizes to microvesicles in the pinealocytes. Localizes to the acrosome in spermatids (By similarity). {ECO:0000250|UniProtKB:Q63564}. |
| Mouse PG classification | NA |
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