| Gene Information | |
|---|---|
| Gene Name | SUV39H1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 412 |
| Protein Names | Histone-lysine N-methyltransferase SUV39H1 (EC 2.1.1.355) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Lysine N-methyltransferase 1A) (Position-effect variegation 3-9 homolog) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) |
| Target Name | lysine n-methyltransferase 1a |
| Target Type | Literature-reported target |
| Gene Age | 454 ( ENSG00000101945 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43463 |
| Gene Card | SUV39H1 |
| Uniprot ID | O43463 |
| Pfam | PF00385; PF05033; PF00856 |
| In ASD | no |
| Allosteric Prediction | yes (0.703462743) |
| Ortholog in Animals | Alpaca_ SUV39H1 ( ortholog_one2one ) Dog_ SUV39H1 ( ortholog_one2one ) GuineaPig_ SUV39H1 ( ortholog_one2one ) Macaque_ SUV39H1 ( ortholog_one2one ) Mouse_ Suv39h1 ( ortholog_one2one ) Pig_ SUV39H1 ( ortholog_one2one ) Rabbit_ SUV39H1 ( ortholog_one2one ) |
| Ohnologs | SUV39H2 |
| Paralogs | KMT2B, ASH1L, NSD3, EHMT2, EZH1, KMT2A, SETBP1, SETD2, SETD1B, SETD1A, SUV39H2, EHMT1, KMT2D, NSD2, SETDB2, EZH2, KMT2C, NSD1, SETDB1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 3MTS (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. Nucleus lamina. Nucleus, nucleoplasm. Chromosome, centromere. Note=Associates with centromeric constitutive heterochromatin. |
| Mouse PG classification | NA |
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