| Gene Information | |
|---|---|
| Gene Name | HCST |
| Organism | Homo sapiens (Human) |
| Gene Length | 93 |
| Protein Names | Hematopoietic cell signal transducer (DNAX-activation protein 10) (Membrane protein DAP10) (Transmembrane adapter protein KAP10) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000126264 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9UBK5 |
| Gene Card | HCST |
| Uniprot ID | Q9UBK5 |
| Pfam | PF07213 |
| In ASD | no |
| Allosteric Prediction | no (-1.415218754) |
| Ortholog in Animals | Alpaca_ HCST ( ortholog_one2one ) Dog_ HCST ( ortholog_one2one ) Macaque_ HCST ( ortholog_one2one ) Mouse_ Hcst ( ortholog_one2one ) Rat_ Hcst ( ortholog_one2one ) Rabbit_ HCST ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | lymph.node, spleen, whole.blood |
| Tissue Specificity | Predominantly expressed in hemopoietic cells such as NK cells, subset of T-cells and monocytes. Detected in leukocytes, spleen, and thymus. {ECO:0000269|PubMed:10528161}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:10426994}; Single-pass type I membrane protein {ECO:0000269|PubMed:10426994}. |
| Mouse PG classification | NA |
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