| Gene Information | |
|---|---|
| Gene Name | CBFB |
| Organism | Homo sapiens (Human) |
| Gene Length | 182 |
| Protein Names | Core-binding factor subunit beta (CBF-beta) (Polyomavirus enhancer-binding protein 2 beta subunit) (PEA2-beta) (PEBP2-beta) (SL3-3 enhancer factor 1 subunit beta) (SL3/AKV core-binding factor beta subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000067955 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q13951 |
| Gene Card | CBFB |
| Uniprot ID | Q13951 |
| Pfam | PF02312 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000378489) |
| Ortholog in Animals | Alpaca_ CBFB ( ortholog_one2one ) Dog_ CBFB ( ortholog_one2one ) Macaque_ CBFB ( ortholog_one2one ) Mouse_ Cbfb ( ortholog_one2one ) Pig_ CBFB ( ortholog_one2one ) Rat_ Cbfb ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.070588(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1CL3 (NMR - ) 1E50 (X-ray 2.60A ) 1H9D (X-ray 2.60A ) 4N9F (X-ray 3.30A ) 6NIL (EM 3.90A ) 6P59 (X-ray 2.94A ) 6VGD (X-ray 4.20A ) 6VGE (X-ray 4.25A ) 6VGG (X-ray 4.31A ) |
| DBSNP | rs1280921900 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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