| Gene Information | |
|---|---|
| Gene Name | SUPT16H |
| Organism | Homo sapiens (Human) |
| Gene Length | 1047 |
| Protein Names | FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000092201 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y5B9 |
| Gene Card | SUPT16H |
| Uniprot ID | Q9Y5B9 |
| Pfam | PF14826; PF00557; PF08512; PF08644 |
| In ASD | no |
| Allosteric Prediction | no (-0.017220914) |
| Ortholog in Animals | Alpaca_ SUPT16H ( ortholog_one2one ) Dog_ SUPT16H ( ortholog_one2one ) GuineaPig_ SUPT16H ( ortholog_one2one ) Macaque_ SUPT16H ( ortholog_one2one ) Mouse_ Supt16 ( ortholog_one2one ) Pig_ SUPT16H ( ortholog_one2one ) Rat_ Supt16h ( ortholog_one2one ) Rabbit_ SUPT16H ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10792464}. |
| Pharmacological Animal Models | 0.082143(Chimpanzee);0.131696(Mouse);NULL(Rat);0.019847(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4Z2M (X-ray 2.98A ) 4Z2N (X-ray 1.92A ) 5E5B (X-ray 1.84A ) 5UMT (X-ray 2.09A ) 5UMU (X-ray 1.90A ) 5XM2 (X-ray 2.19A ) 6UPK (EM 4.90A ) 6UPL (EM 7.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:10421373}. Chromosome {ECO:0000269|PubMed:10421373}. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci. |
| Mouse PG classification | NA |
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