| Gene Information | |
|---|---|
| Gene Name | NFKBIL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 381 |
| Protein Names | NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000204498 ) 3 ( ENSG00000206440 ) 3 ( ENSG00000227565 ) 3 ( ENSG00000234530 ) 3 ( ENSG00000235125 ) 3 ( ENSG00000236196 ) 3 ( ENSG00000236346 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UBC1 |
| Gene Card | NFKBIL1 |
| Uniprot ID | Q9UBC1 |
| Pfam | PF13637 |
| In ASD | no |
| Allosteric Prediction | no (-0.275409503) |
| Ortholog in Animals | Alpaca_ NFKBIL1 ( ortholog_one2one ) Dog_ NFKBIL1 ( ortholog_one2one ) GuineaPig_ NFKBIL1 ( ortholog_one2one ) Macaque_ NFKBIL1 ( ortholog_one2one ) Mouse_ Nfkbil1 ( ortholog_one2one ) Pig_ NFKBIL1 ( ortholog_one2one ) Rat_ Nfkbil1 ( ortholog_one2one ) Rabbit_ NFKBIL1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3130062 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:20829348}. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus. |
| Mouse PG classification | LPG |
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